Xeomin vs Botox vs Dysport vs Jeuveau: Pricing Compared

The short answer

All four are botulinum toxin type A and all four work. Xeomin is the cleanest formulation and the value pick for anyone worried about resistance; Botox is the predictable standard; Dysport spreads further and suits large areas like the forehead; Jeuveau is the cosmetic-only budget option. Compare cost per treated area, never per unit.

Xeomin, Botox, Dysport and Jeuveau at a glance

How they actually differ

Every one of these products is the same active molecule: botulinum neurotoxin type A, which blocks acetylcholine release at the neuromuscular junction so the treated muscle stops contracting. The differences live in what surrounds the molecule and how it is measured.

Botox, Dysport and Jeuveau all ship the toxin bound to accessory complexing proteins. Xeomin strips them out, which is where the nickname "naked toxin" comes from. In practice this has two consequences. Xeomin does not require refrigeration before reconstitution, which simplifies storage, and it presents less foreign protein to the immune system. That matters for the small group of patients who develop neutralising antibodies and stop responding to treatment over years of frequent dosing, and it is the main clinical reason an injector switches someone to Xeomin.

Dysport differs in molecule size and formulation, which makes it diffuse further from each injection point. On a broad flat area like the forehead that is an advantage, because fewer injection points produce a smoother result. Around the eyes or near the brow it is a liability, because unwanted spread is how you get a dropped brow or a heavy lid. Good injectors choose Dysport for surface area and something more contained for precision work.

The unit scale is the single biggest source of confusion in pricing. Dysport units are not Botox units. It takes roughly two and a half to three Dysport units to equal one Botox unit, so a clinic quoting a much lower per-unit price for Dysport is not necessarily cheaper. Xeomin and Jeuveau are dosed roughly one-to-one with Botox, which makes their per-unit prices directly comparable. Jeuveau is the newest and was developed purely for aesthetics, so it has no therapeutic indications and no long clinical history outside cosmetic use, which is part of why practices tend to price it aggressively.

What each one costs

Our pricing dataset covers neurotoxin injections at a median of $11 per unit across 5 med spas, with the typical range from $10 to $11.50 per unit. That per-unit figure is the standard way Botox, Xeomin and Jeuveau are billed, since all three use a comparable unit scale.

We do not hold separate national pricing for Dysport, and quoting a Dysport per-unit figure alongside the others would mislead anyway, because the units are not equivalent. If a practice offers Dysport, ask for the price of the finished treatment area rather than the price per unit.

The honest way to compare quotes is by treated area and by dose. A glabellar treatment typically takes around twenty units of a Botox-scale product, a forehead somewhat less, and crow's feet around twelve per side, though the exact dose is set by muscle mass and by how strong you want the result. Ask any clinic three questions: which product, how many units, and what the total is. A low per-unit price with an inflated unit count is the oldest trick in this category, and flat per-area pricing hides the dose entirely, so a follow-up appointment with a different injector has nothing to work from.

Who should choose which

Choose Xeomin if you have been treated frequently for years and have noticed results fading sooner than they used to, or if you simply want the fewest additives. The absence of complexing proteins is a genuine differentiator for long-term patients, and the per-unit price is usually at or below the Botox equivalent. It is also a sound first choice for anyone who wants a straightforward, comparable unit scale.

Choose Botox if predictability outranks price. It has the longest track record, the widest set of approved cosmetic areas, and almost every injector has more hours with it than with anything else. If you are treating an area where precision matters, or you are new to injectables and want the most documented option, this is the safe pick.

Choose Dysport if you are treating a broad forehead and want smooth coverage from fewer injection points, and you have an injector experienced with its spread. Choose Jeuveau if you are treating frown lines only, price is the deciding factor, and you do not need a product with therapeutic history behind it. Anyone with a neuromuscular condition, or who is pregnant or nursing, should not be treated with any of them.